. Author manuscript; available in PMC: 2011 Jul 27.

Published in final edited form as: Curr Opin Microbiol. 2011 Feb 24;14(2):174–180. doi: 10.1016/j.mib.2011.01.008

Table 1.

Features of pCF10 regulation applicable to functional genomics
Mechanism	pCF10 component(s)	Non-pCF10 example(s)	Considerations
Regulation of promoter	PrgX	Many; some positive regulators	Precise mapping of transcription starts, DNA targets. Cofactors and their effects on regulatory proteins
Change in mRNA 28 structure to affect termination translation, or RNA processing	Q/Anti-Q RNAs	T box, S_MK box, par RNAs, eut riboswitches	Antisense RNA, other RNA-binding ligands
Convergent transcription	prgQ/prgX	RIVET clones	Confirmation and demonstration of function; cis/trans effects