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. 2011 Jul 27;6(7):e21554. doi: 10.1371/journal.pone.0021554

Table 2. Results of in vitro enzyme inhibition assay tests.

COX-1 [%] COX-2 [%]
ID 1 Inline graphic 10 Inline graphic 100 Inline graphic 1 Inline graphic 10 Inline graphic 100 Inline graphic
Inline graphic 2.0 4.2 15± 1.6 19± 2.1 23± Inline graphic 17± 3.2
Inline graphic −3± 3.5 −5± 1.0 26± 23.5 14± 9.7 2.2 1.6
Inline graphic 1.3 12± 3.5 10± 5.1 19± 0.7 10± 1.9 14± 0.1
Inline graphic 10.7 −6± 3.8 −2± 2.8 3.2 7.4 −1± 9.9
Inline graphic 7± 3.9 31± 3.8 72± 4.5 27± 8.1 27± 1.4 38± 3.7
Inline graphic 16± 4.7 18± 9.3 15± 1.6 19± Inline graphic 10.0 12± 2.9
Inline graphic 4.5 8.4 Inline graphic 20± 9.4 13± 8.8 15± 0.3
Inline graphic 4.5 29± 26.8 16± 8.0 14± 2.6 2.1 11± 6.2
Inline graphic 6± 16.8 46± 6.1 89± 1.0 9± 0.7 24± 7.6 38± 3.1
Inline graphic −7± 1.6 −10± 8.5 2.8 5.5 −2± 2.7 −1± 3.7
Inline graphic 11± 12.6 0.6 1.5 2.9 4.2 1.1
Inline graphic 18± 4.0 4.5 14± 1.5 15± 0.1 15± 7.5 19± 2.2

Primed (Inline graphic) compounds are shown in Fig. 8, starred (Inline graphic) compounds are shown in Fig. 9. Discussed compounds are shown in bold face.

For these three measurements, high standard deviations were observed. This could be due to solubility problems, impurities, protein degradation, or other unspecific effects. The corresponding measurements should be treated carefully.