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. 2011 Jul 27;6(7):e22739. doi: 10.1371/journal.pone.0022739

Figure 5. FK866 and HDAC inhibitors synergistically kill primary B-CLL cells.

Figure 5

Primary B-CLL cells were incubated with or without FK866 at the indicated concentrations for 48 h. Thereafter, VA or vorinostat were added at the indicated concentrations. Viability was assessed 48 h later by PI cell staining and flow cytometry. CI values refer to the highest drug concentrations used. CICTs for each drug combination are presented in the lower insets.