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. Author manuscript; available in PMC: 2013 Mar 1.
Published in final edited form as: Mol Carcinog. 2011 Apr 22;51(3):257–267. doi: 10.1002/mc.20780

Table1.

The IC50s of SHR-5 and tumor suppressor gene status in bladder cancer cell lines

Cell lines RT4 UMUC-
3		 T24 5637 J82
Estimated IC50 (μg/ml) 264 100 71 151 165
P53 WT MT/
Exon4		 MT/
Exon5		 MT/
Exon8		 MT/
Exon8
TSC1 HD WT WT WT HD
TSC2 expression weak strong strong strong No detectable

P53: WT= wild-type; MT = mutant allele. Tumor suppressor TSC1: WT = wild-type allele; HD = homozygous deletion.