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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: J Neurosci Res. 2011 Apr 21;89(12):1979–1988. doi: 10.1002/jnr.22650

Fig. 8.

Fig. 8

Assessment of inter-animal variability. Absolute (A) and baseline-normalized (B) O2 consumption rates (OCR) of 14-15 DIV organotypic mouse hippocampal slices exposed to successive additions of respiratory modulators (arrows) are shown for three different wild type mice from the same litter (mean ± SD, n=4 slices for mouse 1 and for mouse 3 and n=2 slices for mouse 2). Slices received successive additions of control (75 μl of aCSF), oligomycin (10 μg/ml), FCCP (5 μM) + pyruvate (10 mM), and antimycin A (10 μM). Two slices from mouse 2 exhibited antimycin A-insensitive respiration exceeding 30% of the total OCR and were excluded from analysis. Rates in B are normalized to the third baseline measurement point.