Table I.
Power analysis of replicates required for observing a 20% difference in bioenergetic parameters
| OCR | # slices for n=5a,b | # slices for n=10a,c |
|---|---|---|
| basal | >12 | 10 |
| oligomycin | >12 | 9 |
| FCCP | 12 | 6 |
| normalized oligomycin (% basal) | 4 | 3 |
| normalized FCCP (% basal) | 5 | 3 |
a
Numbers in columns indicate the number of slices (replicates) per mouse necessary to detect a 20% difference between two groups at a significance level of 0.05 with a power of at least 0.8.
b
Assumes n=5 mice for the two groups
c
Assumes n=10 mice for the two groups