Table 1. Demographic characteristics and fasting morning plasma concentrations of lipids, glucose, insulin, and FABP4 in subgroups of obese and OSA subjects.
Variables | NOB-NOSA (n=90) | NOB-OSA (n=92) | p value | OB-NOSA (n=33) | OB-OSA (n=94) | p value | Overall p value OB vs NOB |
---|---|---|---|---|---|---|---|
Age (yrs) | 7.0 ± 0.68 | 7.1 ± 0.93 | 0.85 | 7.2 ± 1.2 | 7.4 ± 1.2 | 0.54 | 0.002 |
BMI z Score | 0.24 ± 0.86 | 0.07 ± 1.05 | 0.26 | 2.3 ±0.5 | 2.4 ± 0.4 | 0.20 | <0.001 |
AHI (/h TST) | 0.35 ± 0.23 | 4.2 ± 6.2 | <0.001 | 0.34 ± 0.2 | 5.6 ± 6.7 | <0.001 | 0.005 |
FABP4 level (ng/mL) | 7.4 ± 1.67 | 15.3 ± 1.61 | <0.001 | 13.2 ± 2.9 | 23.4 ± 4.7 | <0.001 | <0.001 |
TC (mg/dL) | 155.3 ± 31.9 | 165.1 ± 24.7 | <0.04 | 173.7 ± 25.4 | 186.8 ± 26.5 | <0.05 | 0.56 |
Triglycerides (mg/dL) | 83.2 ± 36.0 | 77.2 ± 41.6 | 0.47 | 110.8 ± 36.1 | 118.5 ± 46.9 | 0.55 | 0.17 |
HDL-C (mg/dL) | 59.1 ± 12.4 | 52.1 ± 9.3 | <0.04 | 48.5 ± 7.5 | 40.6 ± 10.7 | <0.01 | 0.06 |
VLDL-C (mg/dL) | 16.6 ± 12.6 | 19.6 ± 8.4 | <0.01 | 22.4 ± 21.3 | 27.6 ± 9.4 | <0.01 | 0.16 |
LDL-C (mg/dL) | 85.6 ± 27.3 | 94.8 ± 22.6 | <0.01 | 102.9 ± 16.8 | 112.4 ± 21.2 | <0.01 | 0.36 |
Glucose (mg/dL) | 76.8 ± 16.1 | 77.1 ± 15.1 | 0.95 | 83.7 ± 9.8 | 89.8 ± 11.6 | <0.01 | <0.04 |
Insulin (μIU/mL) | 6.5 ± 12.4 | 7.6 ± 13.2 | 0.44 | 11.4 ± 13.6 | 16.2 ± 9.4 | <0.01 | <0.02 |
HOMA-IR | 1.23 ± 0.49 | 1.45 ± 0.49 | 0.003 | 2.36 ± 0.33 | 3.6 ± 0.27 | <0.001 | <0.001 |
BMI, Body mass index; AHI, Obstructive apnea hypopnea index; FABP, Fatty acid binding protein; TC, total cholesterol; HDL-C, High density lipoprotein Cholesterol; VLDL-C, Very low density lipoprotein- Cholesterol; LDL-C, Low density lipoprotein-Cholesterol; P-value was calculated using one way ANOVA.