Table 3. Statistical Comparison Between Core Needle Biopsies and Tumor Resections with Experimental Power.
Epitope | p value | Experiment Sample Size (pair) | Experiment Power | Sample Size Needed to give Power=0.80 (pair) | Coefficient of Variation for Loss of Epitope |
---|---|---|---|---|---|
pAKT | 0.0039 | 10 | 0.93 | 7 | 102% |
AKT | 0.0645 | 10 | 0.74 | 12 | 138% |
pERK | 0.0098 | 10 | 0.98 | 5 | 86% |
ERK | 0.3750 | 10 | 0.21 | 90 | 380% |
pS6K1 | 0.0020 | 10 | 0.99 | 2 | 52% |
S6K1 | 0.2324 | 10 | 0.46 | 26 | 205% |
ER | 0.0273 | 10 | 0.96 | 6 | 93% |
Ki67 | 0.7910 | 10 | 0.10 | 516 | 914% |
GAPDH | 0.4973 | 13 | 0.26 | 79 | 357% |
Pan Cytokeratin | 0.0245 | 14 | 0.88 | 11 | 133% |