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Left: Mesenteric postcapillary venule immediately before and 30 minutes after topical application of MCP-1 (30 ng/ml dissolved in serum-free DMEM). Red arrows, MCs; green arrows, adherent leukocytes. Right: Mesenteric venule 30 minutes after application of MCP-1 in a rat pretreated with RS-102895 (10 μM). Data represent the mean ± SE of 5 rats per group. *P < 0.01 versus corresponding control rats. A complete set of data for this series of experiments is included in the supplement.
