Figure 3.

HRs for coronary heart disease across thirds of waist circumference (A) and waist-to-hip ratio (B) by baseline values of BMI

Analyses were based on 203 338 participants (7750 cases) from 51 studies. Analyses were restricted to participants with BMI of 20 kg/m² or higher. Regression analyses were adjusted for age at baseline and smoking status, and stratified, where appropriate, by sex. Adjusted study-specific log HRs were combined by multivariate random-effects meta-analysis. Y-axes are shown on a log scale. Reference groups are the lowest third of waist circumference or waist-to-hip ratio in the bottom third of BMI. Results were similar for the full BMI range. BMI=body-mass index. HR=hazard ratio.