Table 2. Selected genes differentially expressed in the HP0906 mutant.
Only genes with fold-change ≥2.00, P ≤0.05 and known function are listed in this Table. Fold-changes and P values were calculated based on three independent biological replicates, as described in Methods. Genes discussed in this paper are shown in bold type.
| TIGR ORF number | Annotation | Fold-change | P value |
|---|---|---|---|
| Downregulated genes | |||
| Hp26695-0683 | UDP-N-acetylglucosamine pyrophosphorylase (glmU) | 0.237 | 0.009 |
| Hp26695-1406 | Biotin synthetase (bioB) | 0.386 | 0.004 |
| Hp26695-1206 | Multidrug resistance protein (hetA) | 0.402 | 0.009 |
| Hp26695-0923 | Outer-membrane protein (omp22) | 0.410 | 0.039 |
| Hp26695-1480 | Seryl-tRNA synthetase (serS) | 0.425 | 0.001 |
| Hp26695-0684 | Flagellar biosynthesis protein (fliP) | 0.432 | 0.000 |
| Hp26695-0662 | RNase III (rnc) | 0.440 | 0.013 |
| Hp26695-1208 | Ulcer-associated adenine-specific DNA methyltransferase | 0.451 | 0.003 |
| Upregulated genes | |||
| Hp26695-1315 | Ribosomal protein S19 (rps19) | 2.053 | 0.047 |
| Hp26695-1246 | Ribosomal protein S6 (rps6) | 2.073 | 0.002 |
| Hp26695-1306 | Ribosomal protein S14 (rps14) | 2.082 | 0.030 |
| Hp26695-0084 | Ribosomal protein L13 (rpl13) | 2.167 | 0.035 |
| Hp26695-1310 | Ribosomal protein S17 (rps17) | 2.273 | 0.047 |
| Hp26695-0870 | Flagellar hook (flgE) | 2.407 | 0.008 |
| Hp26695-0115 | Flagellin B (flaB) | 2.432 | 0.007 |
| Hp26695-1314 | Ribosomal protein L22 (rpl22) | 2.464 | 0.009 |
| Hp26695-0824 | Thioredoxin (trxA) | 2.466 | 0.002 |
| Hp26695-0125 | Ribosomal protein L35 (rpl35) | 2.514 | 0.000 |
| Hp26695-0277 | Ferredoxin | 2.550 | 0.008 |
| Hp26695-1076 | Hypothetical protein | 3.374 | 0.007 |