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. Author manuscript; available in PMC: 2011 Jul 28.
Published in final edited form as: Hum Exp Toxicol. 2008 Jun;27(6):513–518. doi: 10.1177/0960327108091861

Table 3.

Summary of atropine toxicity in patients with prospective observations

Ad hoc dose
N=100
Titrated dose
N=126
P Value
Restrained
 Physical 42 (42%) 2 (2%) <0.0001*
 Diazepam 5 (5%) 1 (1%) N/S
 Haloperidol 1 (1%) 0 (0%) N/S
Delirium 17 (17%) 1 (1%) <0.0001*
Hallucination 35 (35%) 1 (1%) <0.0001*
Ventilated 3(3%) 23 (18%) <0.0004*
Hospital stay (days)¥ 4.7 (3-6) 3.1 (2-3) <0.0001*
Deaths from atropine subgroup 7 (7%) 14(11%) N/S
Deaths from whole cohort 8 (7%) 17 (13%) N/S

Delirium was evaluated by using CAM scoring system

Data are number (%) unless otherwise indicated

¥

Median (IQR).

*

Results that are significantly different and corresponding P value