Figure 5.
Oxygen concentration profiles at the average retention time in the microwells in the perfusion culture model shown in Fig. 2. (a) Oxygen concentration at the surface of the cell layers oxygen-impermeable top wall. The inlet velocities of the medium are 1×10−5, 1×10−6, and 1×10−7 m∕s for red, blue, and green lines, respectively. (b) Oxygen concentration profile in the microwells with oxygen-permeable top wall. The inlet velocities of the medium are 1×10−5, 1×10−6, and 1×10−7 m∕s for red, blue, and green lines, respectively. (c) Oxygen concentration profile in the microwells with oxygen-permeable top wall at the x-z plane with 1×10−6 m∕s inlet velocity at 10 560 s.