Table 3.

List of model parameters used in simulations

	wt	E352C	R289C
kv	110	110	90
k−v	50	50	45
ko∗	77	77	41
k−o∗	43	43	28
ki	0.33	0.14	0.13
k−i∗	0.0058	0.0058	0.0058
f∗	0.20	0.20	0.43
g	0.082	0.39	0.001
zv	1.25	1.25	0.32
z−v	−0.1	−0.1	−0.39
z−o∗	−0.41	−0.41	−0.40

Values for k_v, k_−v, k_o, k_−o, k_i, k_−i are given in s⁻¹.

^∗Values that were constrained by experimental measurements (see text and Table S1).