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Mean age of reticulocyte precursors in bone marrow (a) and mean residence time of circulating reticulocytes (b) as functions of time for a typical subject who received subcutaneous recombinant human erythropoietin doses of 20 kIU, 60 kIU and 160 kIU. The curves in (a) and (b) were calculated according to equations 34 and 33, respectively.
