Table 2.
List of additional ECs found in each process from GIPPs.
| Pathway number | Map description | T. cruzi | T. brucei | L. major | EC description |
|---|---|---|---|---|---|
| Translation | |||||
| Map00970 | Aminoacyl-tRNA biosynthesis | 2.1.2.9 | a | b | Methionyl-tRNA formyltransferase |
| 6.1.1.- | 6.1.1.- | 6.1.1.- | O-phosphoseryl-tRNA synthetase | ||
| Replication and repair | |||||
| Map03030 | DNA replication | 3.6.1.- | 3.6.1.- | 3.6.1.- | Hydrolases acting in phosphorus-containing anhydrides |
| Map03410 | Base excision repair | 3.1.-.- | 3.1.-.- | 3.1.-.- | Hydrolases acting on ester bonds |
| 3.1.11.2 | 3.1.11.2 | 3.1.11.2 | Exodeoxyribonuclease III | ||
| Map03420 | Nucleotide excision repair | 2.7.11.22 | 2.7.11.22 | 2.7.11.22 | Cyclin-dependent kinase |
| Map03430 | Mismatch repair | 3.6.1.- | 3.6.1.- | 3.6.1.- | Hydrolases acting in phosphorus-containing anhydrides |
| Map03440 | Homologous recombination | 3.1.-.- | 3.1.-.- | 3.1.-.- | Hydrolases acting on ester bonds |
| Map03450 | Nonhomologous end-joining | 2.7.11.1 | 2.7.11.1 | 2.7.11.1 | Nonspecific serine/threonine protein kinase |
| 2.7.7.7 | 2.7.7.7 | 2.7.7.7 | DNA-directed DNA polymerase | ||
| 3.1.-.- | 3.1.-.- | 3.1.-.- | Hydrolases acting on ester bonds | ||
| 4.2.99.- | 4.2.99.- | 4.2.99.- | Other carbon-oxygen lyases | ||
aPreviously identified by KEGG as entry “Tb11.01.7110”.
bPreviously identified by KEGG as entry “LmjF32.2240”.