TABLE 1.
Clustering of compounds in similar mechanistic classes |
Generation of hypotheses regarding compound action |
Revelation of mechanisms of compound action |
Classification of blinded compounds |
Clustering of compounds by elicited toxicant phenotype |
Ranking and categorization of drug candidates by toxicogenomics signature |
Discerning no effect level for compound transcript effect |
Discovery of biomarkers of toxicity |
Discovery of exposure biomarkers |
Validation/qualification of biomarker signatures |