Table 2.
Cross-sectional associations of proteins in the pentraxin family with eGFRcys among MESA participantsa
| Model 1 | P | Model 2 | P | Model 3 | P | |
|---|---|---|---|---|---|---|
| PTX3 | − 1.65 (− 2.4, − 0.91) | < 0.001 | − 1.5 (− 2.2, − 0.79) | < 0.001 | − 1.39 (− 2.1, − 0.68) | < 0.001 |
| CRP | − 3.52 (− 4.3, − 2.8) | < 0.001 | − 0.90 (− 1.7, − 0.09) | 0.03 | − 0.07 (− 1, 0.82) | 0.89 |
| SAP | − 2.5 (− 3.2, − 1.7) | < 0.001 | − 0.53 (− 1.3, 0.23) | 0.17 | − 0.13 (− 0.91, 0.64) | 0.74 |
a
β coefficients represent difference in eGFRcys (mL/min/1.73 m2) per SD increase in lnPTX3, lnSAP and lnCRP, with 95% confidence intervals.
Model 1 = age, gender, yearly income; Model 2 = Model 1 + HTN, diabetes, impaired fasting glucose, current smoking, ACE inhibitor use, statin use, LDL, HDL, triglycerides; Model 3 = Model 2 + IL-6.