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Increased accumulation of AGEs and acrolein adducts in the plasma of HF fed mice. Western blots of plasma from NC and HF fed WT and akr1b3-null mice were probed with (A) anti-AGEs and (B) anti-acrolein antibodies. Bar graphs show the intensity of indicated anti-AGEs and anti-acrolein positive bands normalized to Amido-Black stained blots. Data are presented as mean ± S.E.M. *P < 0.01 vs WT (NC).
