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. Author manuscript; available in PMC: 2012 Jul 15.
Published in final edited form as: Biochem Biophys Res Commun. 2011 May 4;410(4):707–713. doi: 10.1016/j.bbrc.2011.04.133

Fig 4. Analysis of M-TTR species in solution by gel filtration.

Fig 4

Mixtures of the monomeric M-TTR (16 μM, i.e. 4 μM of tetramer equivalent) and compounds 1 and 5 (4μM) were incubated for 24h at 37°C under the same conditions as in the cell-based assay. Samples were analyzed at time 0 and time 24h by gel filtration (Superdex 75). Chromatograms are shown for A) M-TTR, B) M-TTR + resveratrol (1), and C) M-TTR + 5. Dashed traces: time 0; solid traces: time 24h.