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. Author manuscript; available in PMC: 2011 Jul 28.
Published in final edited form as: Langmuir. 2007 Jan 23;23(8):4103–4107. doi: 10.1021/la0630559

Fig. 3. Parallel screening of multiple cell configurations.

Fig. 3

(A) Glass coverslip with patterned photoresist (PEG mask) illustrating the variety of designs possible on a single substrate. Scale bar is 2 mm. (B) Phase contrast image showing variations in hepatocyte-fibroblast separation (day 6). (C and D) Spatially restricted contact between hepatocytes and fibroblasts (day 6). (E) Phase contrast and fluorescence overlay showing expression of intracellular albumin in green after 8 days of culture, indicating retained hepatocyte function. This in situ assay identifies an interesting experimental condition that can be further pursued in larger formats. (B-E) Scale bars are 200 μm.