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Cell cycle distribution of MCF-7 cells prior to BaP treatment
| Cell cycle distribution (%) | ||||
|---|---|---|---|---|
| Culture manipulations (time, h) | G0/G1-phase | S-phase | G2/M-phase | |
| G0/G1-enriched | 48 h serum deprivation | 65.3 ± 2.1 | 14.1 ± 2.4 | 20.6 ± 2.4 |
| S-enriched | 18 h after 48 h serum deprivation | 24.7 ± 4.2 | 55.7 ± 8.2 | 19.5 ± 4.0 |
| G2/M-enriched | 12 h colchicine (0.25 μM) after 24 h aphidicolin (1 μg/mL) | 8.9 ± 2.2 | 18.2 ± 4.1 | 72.9 ± 5.9 |
Cells were manipulated to generate: G0/G1-, S-, and G2/M-enriched cultures.
