Table 4.
Univariate and Multivariate Analyses of Factors Associated With Survival and Recurrence
| Factor | OS | DFS | ||||||
|---|---|---|---|---|---|---|---|---|
| Multivariate | Multivariate | |||||||
| Univariate P | Hazard Ratio | 95% CI | P | Univariate P | Hazard Ratio | 95% CI | P | |
| Age: ≤ 50 v >50 years | 0.603 | NA | 0.782 | NA | ||||
| Sex: female v male | 0.197 | NA | 0.254 | NA | ||||
| Liver cirrhosis: no v yes | 0.932 | NA | 0.194 | NA | ||||
| Tumor size: ≤ 50 v >50 mm | 0.001 | 2.727 | 1.326-5.605 | 0.006 | 0.001 | 2.175 | 1.22-3.875 | 0.008 |
| AFP: ≤ 20 v >20 ng/ml | 0.051 | NA | 0.070 | NS | ||||
| HBsAg: positive v negative | 0.141 | NA | 0.042 | NS | ||||
| TNM stage: I-II v III | 0.002 | NS | υ0.0001 | 1.982 | 1.288-3.366 | 0.005 | ||
| Tumor number: single v multiple | 0.017 | NS | 0.0001 | NS | ||||
| Tumor encapsulation: complete v uncomplete v no | 0.051 | NA | 0.065 | NA | ||||
| Vein invasion: yes v no | 0.001 | 1.713 | 0.927-3.167 | 0.086 | υ0.0001 | NS | ||
| Intratumoral ZBTB20: low v high | 0.001 | 1.952 | 1.134-3.359 | 0.016 | 0.0000 | 2.094 | 1.296-3.383 | 0.003 |
| Peritumoral ZBTB20: low v high | 0.225 | NA | 0.002 | NS | ||||
Abbreviations: OS, overall survival; DFS, disease-free survival; NA, not adopted; HBsAg, hepatitis B s antigen; NS, not significant.