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. 2011 Jul 6;108(30):12390–12395. doi: 10.1073/pnas.1107103108

Fig. 4.

Fig. 4.

A neuronal-specific requirement for dNab2 in normal behavior. (A) Locomotor phenotypes of genomic alleles and tissue-specific RNAi of dNab2. Data are presented as the average percentage of flies that reach the top of a cylinder after 5 s across all trials. Groups of 10 5-d-old flies were tested for at least 10 independent trials per genotype (*P = 8.36 × 10−9 and **P = 8.38 × 10−9 in a two-tailed t test). Error bars = SEM. (B and C) Pan-neuronal expression of dNab2 rescues both eclosion and locomotor defects. (B) Table summarizing the percentage of flies eclosed (of expected) for indicated genotypes. (C) For the locomotor assay, data are presented as the average percentage of flies that reaches the top of a cylinder after indicated time points across all trials. Groups of 10 2-d-old flies were tested for at least 10 independent trials per genotype (*P = 5.12 × 10−13, **P = 6.59 × 10−13, ***P = 1.97 × 10−7, and ****P = 0.002 in a two-tailed t test). Error bars = SEM.