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. 2011 Jul 28;6(7):e22907. doi: 10.1371/journal.pone.0022907

Figure 7. The effect of Eos on γ- to β-globin gene switching during erythroid differentiation.

Figure 7

(A) Kinetics of γ- and β-globin gene expression during the erythroid maturation of CD34+ HPCs. “Eos” represents CD34+ HPCs infected with lentiviruses carrying Eos. (B) Ratio of γ to [γ+β] mRNA during the erythroid maturation of CD34+ HPCs. Quantitative real-time PCR assays were performed in triplicate and were normalized to β-actin mRNA levels. Data were obtained from three independent experiments, and error bars represent standard deviation. *P<0.05, #P<0.01.