Table 3.
Infant characteristics, indicators of hypotension, and indicators of white matter damage and cerebral palsy diagnosis (row percents).
| Characteristics of the infant | Hypotension indicator | Indicators of white matter damage | Cerebral palsy | N | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Low Q§ | Vaso¶ | Labile† | VM | EL | Q | D | H | |||
| Sex | Male | 21 | 26 | 25 | 12 | 8 | 7 | 4 | 3 | 544 |
| Female | 20 | 22 | 23 | 8 | 6 | 5 | 3 | 1 | 497 | |
| Type of gestation | Singleton | 21 | 21 | 26 | 10 | 7 | 6 | 4 | 2 | 690 |
| Multiple | 20 | 30 | 20 | 11 | 7 | 7 | 3 | 2 | 351 | |
| Gestational age (weeks) | 23–24 | 19 | 35 | 28 | 14 | 10 | 13 | 8 | 3 | 209 |
| 25–26 | 20 | 12 | 24 | 11 | 7 | 5 | 2 | 2 | 480 | |
| 27 | 24 | 20 | 21 | 7 | 5 | 3 | 3 | 1 | 352 | |
| Birth weight (grams) | ≤ 750 | 20 | 29 | 28 | 11 | 7 | 9 | 5 | 3 | 383 |
| 751–1000 | 23 | 23 | 23 | 8 | 7 | 4 | 2 | 2 | 458 | |
| ≥ 1000 | 18 | 18 | 18 | 13 | 9 | 6 | 4 | 1 | 200 | |
| BW Z-score* | < -2 | 25 | 21 | 32 | 7 | 2 | 2 | 0 | 5 | 56 |
| ≥ -2, < -1 | 20 | 24 | 29 | 11 | 2 | 6 | 3 | 1 | 141 | |
| ≥ -1 | 21 | 24 | 22 | 7 | 8 | 6 | 4 | 2 | 844 | |
| HC Z-score* | < - 2 | 26 | 27 | 28 | 7 | 2 | 5 | 0 | 4 | 82 |
| ≥ -2, < -1 | 21 | 21 | 24 | 8 | 6 | 6 | 5 | 1 | 234 | |
| ≥ -1 | 20 | 24 | 23 | 12 | 8 | 7 | 4 | 2 | 690 | |
| SNAP-II | < 20 | 13 | 16 | 21 | 7 | 6 | 5 | 2 | 1 | 536 |
| 20–39 | 24 | 24 | 24 | 10 | 8 | 7 | 5 | 2 | 256 | |
| ≥ 30 | 35 | 44 | 31 | 17 | 8 | 9 | 6 | 3 | 232 | |
| Max number of infants | 216 | 252 | 247 | 105 | 73 | 64 | 37 | 19 | 1041 | |
| Row percent | 21 | 24 | 24 | 10 | 7 | 6 | 4 | 2 | ||
§
Low Q: lowest MAP recorded in the first 24 hours, in the lowest quartile for gestational age
¶
Vaso: treatment for hypotension with a vasopressor in the first 24 hours with any vasopressor (dopamine, dobutamine, and epinephrine)
†
Labile: labile blood pressure, defined as the upper quartile of the difference in the lowest and highest MAP
VM=Moderate/Severe ventriculomegaly; EL=Echolucenct lesion
Q=Quadriparesis; D= Diparesis; H=Hemiparesis
SNAP-II=Score for Neonatal Acute Physiology II