Table 4.

Lipophilicity and cell membrane permeability of cyclic nucleotide analogs

Lipophilicity is expressed as partition coefficient (log K _w) of the analog between methanol and water. Permeability represents percentage of intracellular measured cyclic nucleotide content as a function of external applied concentration

^aKrass et al. (1997)

^bBartsch et al. (2003)