Table 2.
Parameter estimates between control and Ca2+ channel blockade condition during 0.05 and 0.10 Hz OLBNP
0.10 Hz | 0.05 Hz | 2 × 2 RMANOVA | |||||
---|---|---|---|---|---|---|---|
Control | Blockade | Control | Blockade | Freq | Con | Freq × Con | |
Windkessel model | |||||||
Capacitive gain (cm mmHg−1) | 1.7 ± 0.30 | 1.8 ± 0.58 | 1.6 ± 0.87 | 1.4 ± 0.60 | 0.23 | 0.94 | 0.40 |
Conductive gain (cm s−1 mmHg−1) | 0.022 ± 0.077 | 1.8 ± 0.58 | −0.008 ± 0.21 | 0.20 ± 0.35 | 0.60 | <0.05 | 0.28 |
R2 | 0.99 ± 0.016 | 0.99 ± 0.0097 | 0.91 ± 0.065 | 0.89 ± 0.068 | — | — | — |
Normalised Windkessel model | |||||||
Capacitive gain (% s−1 mmHg−1) | 2.3 ± 0.45 | 2.9 ± 0.87 | 2.4 ± 1.2 | 2.3 ± 0.93 | 0.38 | 0.58 | 0.22 |
Conductive gain (% mmHg−1) | 0.11 ± 0.36 | 0.13 ± 0.10 | −0.038 ± 0.32 | 0.27 ± 0.51 | 0.96 | <0.05 | 0.26 |
R2 | 0.97 ± 0.03 | 0.99 ± 0.0044 | 0.91 ± 0.069 | 0.89 ± 0.067 | — | — | — |
Conductance model | |||||||
Conductive gain (cm s−1 mmHg−1) | 0.82 ± 0.32 | 0.96 ± 0.35 | 0.21 ± 0.32 | 0.48 ± 0.40 | <0.05 | <0.05 | 0.17 |
R2 | 0.53 ± 0.23 | 0.64 ± 0.22 | 0.34 ± 0.31 | 0.42 ± 0.33 | — | — | — |
Normalised conductance model | |||||||
Conductive gain (% mmHg−1) | 1.1 ± 0.35 | 1.5 ± 0.49 | 0.31 ± 0.47 | 0.71 ± 0.52 | <0.05 | <0.05 | 0.91 |
R2 | 0.97 ± 0.031 | 0.89 ± 0.068 | 0.91 ± 0.069 | 0.99 ± 0.005 | — | — | — |
Freq, frequency; Con, drug condition; Freq × Con, interaction.