Table 2.
C2 Gene Sets Changes in CHF1 Transgenic Hearts versus Wild-type Hearts after Banding
| Name | p-Value | FDR | Size | Score |
|---|---|---|---|---|
| Downregulation | ||||
| MCALPAINPATHWAY | 0 | 0 | 23 | −0.5048976 |
| AGPCRPATHWAY | 0 | 0 | 12 | −0.6601133 |
| ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY | 0 | 0 | 32 | −0.3123639 |
| BADPATHWAY | 0 | 0 | 19 | −0.6192746 |
| YAMA_RECURRENT_HCC_UP | 0 | 0 | 10 | −0.8839298 |
| SHHPATHWAY | 0 | 0 | 13 | −0.7455815 |
| CELL_GROWTH_AND_OR_MAINTENANCE | 0 | 0 | 59 | −0.274771 |
| SIG_CHEMOTAXIS | 0 | 0 | 44 | −0.3581732 |
| BCL2_FAMILY_AND_REG_NETWORK | 0 | 0 | 21 | −0.4430197 |
| BECKER_CANCER_ASSOCIATED_SUBSET_2 | 0 | 0 | 12 | −0.6853539 |
| TUMOR_SUPRESSOR | 0 | 0 | 20 | −0.5595032 |
| MITOCHONDRIAPATHWAY | 0 | 0 | 20 | −0.3626908 |
| CELL_CYCLE_CHECKPOINT_II | 0 | 0 | 8 | −0.7899912 |
| CHREBPPATHWAY | 0 | 0 | 16 | −0.5171871 |
| LINDSTEDT_DEND_8H_VS_48H_DN | 0 | 0 | 58 | −0.3669714 |
| HDACI_COLON_TSABUT_DN | 0 | 0 | 16 | −0.6385193 |
| UVC_HIGH_D7_DN | 0 | 0 | 29 | −0.469932 |
| HDACI_COLON_SUL2HRS_UP | 0 | 0 | 11 | −0.8317397 |
| FSH_OVARY_MCV152_DN | 0 | 0 | 41 | −0.6036231 |
| Upregulation | ||||
| RNA_POLYMERASE | 0 | 0 | 12 | 1.0778809 |
| AGUIRRE_PANCREAS_CHR22 | 0 | 0 | 55 | 0.7075367 |
| SMITH_HTERT_DN | 0 | 0 | 61 | 0.2820412 |
| SELENOAMINO_ACID_METABOLISM | 0 | 0 | 12 | 0.6277189 |
| ASTON_DEPRESSION_DN | 0 | 0 | 133 | 0.21018 |
| ASTON_OLIGODENDROGLIA_MYELINATION_SUBSET | 0 | 0 | 14 | 0.5149096 |
| YAO_P4_KO_VS_WT_UP | 0 | 0 | 80 | 0.3353383 |
| CMV-UV_HCMV_6HRS_DN | 0 | 0 | 91 | 0.2841596 |
| GAMMA-UV_FIBRO_DN | 0 | 0 | 37 | 0.2858421 |
| CREB_BRAIN_8WKS_DN | 0 | 0 | 42 | 0.5487613 |
| IGF_VS_PDGF_UP | 0 | 0 | 64 | 0.4450024 |
| TSA_CD4_DN | 0 | 0 | 17 | 0.6375096 |
| ET743_HELA_DN | 0 | 0 | 16 | 0.65793 |
| OLDONLY_FIBRO_UP | 0 | 0 | 34 | 0.3175369 |
| 4NQO_UNIQUE_FIBRO_DN | 0 | 0 | 8 | 0.9573262 |
| ZMPSTE24_KO_DN | 0 | 0 | 26 | 0.6011035 |
| IFN_GAMMA_UP | 0 | 0 | 37 | 0.5207427 |