Table 6.
Comparison of miRNA profiling studies on endometriosis
| Tissue types | Menstrual cycle phase | Platform | miRBase version | Stage of disease | Down | Up | Reference |
|---|---|---|---|---|---|---|---|
| Four paired eutopic-ectopic, four ectopic | Early/mid secretory | mirVana miRNA probe set | Not listed | Stage 3 | Every miRNA down | Not listed | (93) |
| Eight paired eutopic-peritoneal ectopic | Proliferative and secretory | mirVana miRNA probe set | Not listed | ASRM II-IV | 196b, 20a, 34c, 424, 142-3p, 200b, 141, 200a | 145, 143, 99a, 99b, 126, 100, 125b, 150, 125a, 223, 194, 365, 29c, 1 | (118) |
| Four eutopic endometrium endometriosis, four eutopic non-endometriosis | Early secretory | Exiqon LNA array | miRBase 10 | Moderate-severe | 9, 9*, 34b*, 34c-5P, 34c-3p | None | (120) |
| Sixteen paired eutopic-endometrioma | Proliferative | LC Sciences | miRBase 9.1 | Moderate-severe | 106a, 106b, 130b, 132, 17-5p, 182, 183, 196b, 200a, 200b, 200c, 20a, 25, 375, 425-5p, 486, 503, 638, 663, 671, 768-3p, 768-5p, 93 | 1, 100, 101, 126, 130a, 143, 145, 148a, 150, 186, 199a, 202, 221, 28, 299-5p, 29b, 29c, 30e-3p, 30e-5p, 34a, 365, 368, 376a, 379, 411, 493-5p, 99a | (119) |
| Nine eutopic normal; 10 endometrioma | Varied | Illumina Next Generation Sequencing | miRBase 15 | Moderate-severe | 504, 141, 873, 429, 203, 449b, 200b, 375, 200c, 10a, 200a, 34c-5p | 202, 708, 193-3p, 29c, 509-3-5p, 193a-5p, 574-3p, 100, 485-3p, 720 | (92) |