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. 2011 May 5;25(8):1257–1279. doi: 10.1210/me.2011-0099

Table 8.

miRNA that play a functional role in uterine leiomyomata

miRNA Cell type studied Function Reference
miR-23a/b, miR-145, miR-197, miR-411, miR-412, let-7 Uterine leiomyomata Higher expression in uterine leiomyomata of black women (142)
let-7 family Uterine leiomyomata Higher expression in uterine leiomyomata <3 cm (142, 148)
let-7c, let-7 family Uterine leiomyomata; primary leiomyoma cultures Regulates HMG2A (142, 148, 149)
miR-21 Myometrial, smooth muscle, spontaneously transformed leiomeiomata, leiomyosarcoma cell lines Regulates E2F1, PDCD4, PTEN, TGF-BRII; regulates proliferation and apoptosis under steroid hormone regulation (150)