Table 1. Summary of genes whose expression is significantly altered in Ad-ANGPT2-infected myoblasts as compared with cells infected with Ad-GFP viruses.

Genes induced by ANGPT2 in skeletal myoblasts
Accession	Symbol	Definition	Ad-ANGPT2/	Function
			Ad-GFP
NM001024629	NRP1	Neuropilin 1 transcript variant 3	12.9	Angiogenesis
NM016111	TELO2	Telomere maintenance 2 homology	12.0	Cell cycle
NM201414	APP	Amyloid beta A4 precursor	8.9	Apoptosis
NM033397	ITPRIP	Inositol triphosphate interacting protein	3.2	Signaling
NM032340	C6orf125	Chromosome 6 open reading frame 125	3.1	Carbohydrase transport
NM000230	LEP	Leptin	3.1	Signaling
NM182480	COQ6	Coenzyme Q6 homolog	2.9	Electron transport
NM181877	ZSCAN2	Zinc finger and SCAN domain containing 2	2.8	Transcription
NM032645	C10orf33	Chromosome 10 open reading frame 33	2.7	Electron transport
NM032645	RAPSN	Receptor-associated protein of synapse	2.6	Proteolysis
NM016401	C11orf73	Chromosome 11 open reading frame 73	2.6	Unknown
NM001011539	LOC44104	Hypothetical LOC441046	2.5	Metabolism
NM199295	APITD1	Apoptosis-induced TAF9-like domain 1	2.5	Transcription
Genes inhibited by ANGPT2 in skeletal myoblasts
NM002155	HSPA6	Heat shock 70 kDA protein 6	0.03	Protein folding
NM178539	FAM19A2	Family with sequence similarity 19	0.05	Signaling
NM001012977	PAP1M	Polyadenylate-binding protein 1	0.05	RNA stability
NM005345	HSPA1A	Heat shock 70 kDA protein 1A	0.16	Protein folding
NM139016	C20orf198	Chromosome 20 open reading frame 198	0.20	Unknown
NM005346	HSPA1B	Heat Shock 70 kDa protein	0.21	Protein folding
NM001002796	MCTP1	Multiple C2 domains, transmembrane 1	0.21	Ca++-mediated signaling
NM005252	FOS	FBJ murine osteosarcome oncogene homolog	0.22	Transcription
NM032461	SPANXB1	Spanx family, member B1	0.26	Transcription
NM153292	NOS2A	Nitric oxide synthase 2A	0.26	Signaling
NM030926	ITM2C	Integral membrane protein 2C	0.26	Unknown
NM013453	SPANXA1	Spanx family member A1	0.27	Transcription
NM000488	SERPINC1	Serine peptidase inhibtor, clade C	0.27	Apoptosis
NM172220	CSF3	Colony stimulating factor 3	0.28	Immune responses
NM018602	DNAJA4	DNAJ (Hsp40) homolog	0.28	Protein folding
NM022661	SPANXC	Spanx family member C	0.28	Transcription
NM001005611	EDA	Ectodysplasin A	0.29	Immune responses