Table 1.

RRRM through catalytic enantioselective silylation

entry	substrate	A (ee)	B (ee)	yield (comb.)	ratio A/B
(1)				92%a	50/50
(2)				89%b	58/42
(3)				89%c	64/36
(4)				90%d	50/50
(5)				75%e	52/48
(6)				50%f	52/48

Conditions:

^aTBSCl (2 equiv), DIPEA (1 equiv), toluene [1 M], -30 °C, 120 h.

^bTBSCl (1.5 equiv), DIPEA (1 equiv), toluene [1 M], -60 °C, 120 h.

^cTBSCl (1.5 equiv), DIPEA (1 equiv), toluene [1 M], -30 °C, 120 h.

^dTESCl (1.5 equiv), DIPEA (1 equiv), THF [1 M], -60 °C, 72 h.

^eTBSCl (1 equiv), DIPEA (1 equiv), toluene [1 M], -60 °C, 120 h.

^fTBSCl (1 equiv), DIPEA (1.25 equiv), THF [1 M], -30 °C, 110 h.