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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Neuropharmacology. 2011 Mar 4;62(2):695–704. doi: 10.1016/j.neuropharm.2011.02.023

Table 1.

Summary of human clinical findings with the AX+/BX− paradigm.

Fear Learning (AX+ > NA) Safety Signal Learning (BX−< AX+) Safety Signal Transfer (AB < AX+)

Healthy volunteers Yes Yes Yes
Combat PTSD Yes Yes/No No
Civilian PTSD Yes No No
Depression w PTSD Yes No No
Depression w/o PTSD Yes Yes Yes