Skip to main content
. 2011 Mar 24;17(7-8):665–675. doi: 10.2119/molmed.2011.00018

Figure 4.

Figure 4

OPLS-DA of gene level normalized exon expression (splice index) of the filtered data set for all human exons. The exons are color coded according to significant exons included in TGFβ analysis in Figure 2: TAV-specific (blue), BAV-specific (green), and common (red) probe sets. (A) Combined model scatter plot based on TAV dilated versus nondilated and BAV dilated versus nondilated OPLS-DA models. The black diagonal is aimed for interpretation purposes. Bar plots showing the loadings of each of the significant exons indicating their contribution to the first PC are shown in (B–D) and color coded according to (A). The confidence levels for each data point were estimated by a jack-knife algorithm. Exons chosen for RT-PCR validation are marked in (A–D).