Fig. 2.

Modulation of astroglial proliferation by nucleotides in highly enriched astroglial cultures (a, c) and co-cultures (b, d). Cultures were incubated with nucleotides or solvent for 48 h and methyl-[³H]-thymidine (1 μCi/ml) was added in the last 24 h. Cell proliferation was estimated by methyl-[³H]-thymidine incorporation and expressed in percentage of control. Values are means ± SEM from five to seven experiments. *P < 0.05, significant differences from control (solvent)