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. 2011 May 13;88(5):621–627. doi: 10.1016/j.ajhg.2011.04.007

Figure 1.

Figure 1

Clinical Phenotype and Segregation Analysis in a German Family Affected by Hereditary Hearing Loss

(A) Audiograms of selected family members (red indicates the right ear, and blue indicates the left ear). Hearing loss in males typically starts between ages 3–7, whereas hearing loss in females begins in the second to third decades.

(B) Haplotypes constructed by four Xp22.12 SNP markers mapped the disease locus between rs1482816 (hg19 X: 5746140) and rs1557901 (hg 19 X: 23222925). Individuals I-1–I-4, III-4, III-6, IV-1, and V-1 were not subjected to the 10K GeneChip linkage analysis.