Table 6.

Predicted Risk of Prostate Cancer in Men Having One Affected First-Degree Relative

Percentile	Lifetime Risk (95% CI)	Incidence Rate Ratio (95% CI)	10-Year Risk at Age 50 (95% CI)	10-Year Risk at Age 60 (95% CI)	NNS	Age at which 10-Year Risk > 2.11%
5	0.103 (0.100–0.118)	0.71 (0.68–0.82)	0.015 (0.014–0.017)	0.042 (0.041–0.048)	2282	52.6
10	0.128 (0.125–0.142)	0.89 (0.87–1.00)	0.019 (0.018–0.021)	0.053 (0.052–0.059)	1818	50.8
20	0.163 (0.161–0.174)	1.17 (1.15–1.26)	0.025 (0.024–0.026)	0.069 (0.067–0.074)	1401	49.0
30	0.192 (0.190–0.200)	1.41 (1.39–1.48)	0.030 (0.029–0.031)	0.082 (0.081–0.086)	1172	47.9
40	0.219 (0.218–0.225)	1.64 (1.63–1.69)	0.034 (0.034–0.035)	0.095 (0.094–0.098)	1012	47.0
50	0.246 (0.246–0.249)	1.89 (1.88–1.91)	0.039 (0.039–0.040)	0.108 (0.108–0.110)	887	46.3
60	0.275 (0.274–0.275)	2.16 (2.16–2.16)	0.045 (0.045–0.045)	0.123 (0.123–0.123)	780	45.6
70	0.308 (0.303–0.309)	2.50 (2.44–2.50)	0.052 (0.051–0.052)	0.140 (0.138–0.141)	684	44.9
80	0.348 (0.338–0.350)	2.94 (2.82–2.96)	0.061 (0.058–0.061)	0.163 (0.157–0.164)	589	44.1
90	0.406 (0.389–0.410)	3.65 (3.43–3.70)	0.075 (0.070–0.076)	0.198 (0.187–0.201)	484	43.2
95	0.456 (0.432–0.461)	4.36 (4.00–4.43)	0.089 (0.082–0.090)	0.232 (0.215–0.235)	414	42.4

The incidence rate ratio is computed with reference to the general population. The following abbreviations are sued: CI, confidence interval; NNS, number of individuals that need to be screened in order to prevent one cancer death.