Table 7.
Application of the Three Methods to the Crohn Disease Meta-Analysis Results of Franke et al.12
| SNP | Chromosome | Position | FE p Value | RE p Value | New RE p Value | I2 |
|---|---|---|---|---|---|---|
| rs4656940 | 1 | 159,096,892 | 1.05 × 10−6 | 6.89 × 10−4 | 6.91 × 10−7 | 57.01 |
| rs3024505 | 1 | 205,006,527 | 7.03 × 10−9 | 5.29 × 10−5 | 5.49 × 10−9 | 46.49 |
| rs780093 | 2 | 27,596,107 | 1.12 × 10−4 | 5.95 × 10−2 | 2.78 × 10−5 | 61.85 |
| rs17309827 | 6 | 3,378,317 | 5.62 × 10−6 | 1.00 × 10−4 | 4.98 × 10−6 | 22.98 |
| rs17293632 | 15 | 65,229,650 | 6.17 × 10−13 | 2.11 × 10−6 | 3.41 × 10−13 | 52.11 |
| rs151181 | 16 | 28,398,018 | 3.32 × 10−10 | 3.80 × 10−6 | 3.08 × 10−10 | 35.22 |
The boldface denotes the top p value among three methods. Only the six SNPs at which new RE achieves the top p value are shown in the table. See Table S1 for all 69 SNPs tested.