Table 1. Number of randomized, placebo-controlled statin trials that recorded LDL reduction, and percentage of LDL reduction achieved.
LDL reduction was calculated by subtracting the levels post-treatment with pre-treatment values in the statin cohort(88–93,95–97,99–102,104,106,107,109,110,113–117,119–122,124–128,130–132,135,136). In some studies, the placebo group also demonstrated LDL reduction. In these cases this value was subtracted from the reduction achieved in the treatment group.
Statin Trials | Number of studies | LDL reduction (%) |
---|---|---|
| ||
Pravastatin | 14 | 24.3 ± 6.5 |
Simvastatin | 6 | 32.6 ± 8.8 |
Atorvastatin | 6 | 33.4 ± 8.9 |
Fluvastatin | 4 | 25.5 ± 9.3 |
Lovastatin | 3 | 30.6 ± 8.6 |
Rosuvastatin | 1 | 41 |