Table 4.
Mixed longitudinal regression analyses of determinants of HDL-C (model 1), triglycerides (model 2), insulin (model 3), and proinsulin (model 4) in infants and children of South Asian and European origin: the Manchester Children's Growth and Vascular Health study
| Dependent variables |
||||||||
|---|---|---|---|---|---|---|---|---|
| HDL-C (model 1) |
Triglycerides (model 2) |
Ln insulin (model 3) |
Ln Proinsulin (model 4) |
|||||
| β | 95% CI | β | 95% CI | β | 95% CI | β | 95% CI | |
| Explanatory variables | ||||||||
| Age (months) | 0.02 | −0.09 to 0.14 | −0.32a | −0.57 to −0.08 | −0.84a | −1.52 to −0.16 | 0.30 | −0.07 to 0.68 |
| Sexd | 0.02 | −0.07 to 0.11 | −0.08 | −0.26 to 0.10 | 0.09 | −0.42 to 0.60 | −0.13 | −4.1 to 0.43 |
| BMI (kg/m2) | 0.04b | 0.02 to 0.07 | 0.50 | 0.00 to 0.10 | 0.01 | −0.17 to 0.19 | −0.01 | −0.10 to 0.09 |
| Length/height (cm) | 1.31b | 0.37 to 2.25 | 1.11 | −0.80 to 3.03 | 4.39 | −1.61 to 10.40 | −4.07a | −7.32 to −0.82 |
| Ethnicitye | 0.05 | −0.06 to 0.15 | 0.01 | −0.19 to 0.20 | 0.30 | −0.28 to 0.89 | −0.19 | −0.51 to 0.12 |
| Adiponectin (mg/liter) | 0.04c | 0.02 to 0.05 | −0.01 | −0.04 to 0.02 | −0.004 | −0.09 to 0.08 | 0.01 | −0.03 to 0.06 |
Data are β-coefficient and 95% CI. Insulin and proinsulin are Ln transformed before inclusion as dependent variables in models. P values are for independent variables in model values.
P < 0.05.
P < 0.01.
P < 0.001.
Females are reference group in model.
Europeans are reference group in model.