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. 2011 Jan 1;5(2):79–89. doi: 10.1186/1479-7364-5-2-79

Table 3.

Summary of strongest associations by phenotype (p-value cut-off with Bonferroni correction: 3.6 × 10-4)

Gene Chr. location(mB) SNP Phenotype Model Group Uncorrected p-value
SPTBN1 2; 54.7M rs3287 SI Recessive All 5.8 × 10-5
SPTBN1 2; 54.7M rs3287 SI Genotypic All 1.9 × 10-4
HERC1 15; 61.7M rs12439722 SI Genotypic All 5.4 × 10-4
TRPA1 8; 73.1M rs1373302 AIRg Dominant All 9.7 × 10-5
PLXNA4 7; 131.5M rs2671110 AIRg Recessive AA 1.4 × 10-4
HERC1 15; 61.7M rs12439722 FI Recessive All 2.8 × 10-4
HERC1 15; 61.7M rs12439722 FI Genotypic All 1.4 × 10-4
HERC1 15; 61.7M rs12439722 HOMA-IR Recessive All 8.0 × 10-4
HERC1 15; 61.7M rs12439722 HOMA-IR Genotypic All 4.8 × 10-4

Covariates: age, sex, Tanner stage, socioeconomic status, European admixture, Amerindian admixture, height, total fat (for acute insulin response to glucose, control for SI as well). SNP, single nucleotide polymorphism; SPTBN1, spectrin, beta, non-erythrocytic 1; PLXNA4, plexin A4.