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. 2011 Jul 11;12:65. doi: 10.1186/1471-2202-12-65

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Copyright ©2011 Kisiel et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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jaguar loss of function mutants exhibited defects in basal synaptic transmission. Electrophysiological recordings from muscles 6/7 of third instar larvae revealed EJP amplitude was significantly reduced in the most severe jar mutant, jar³²²/Df(3R)crb87-5 MN, compared to the control (Dunnett's Multiple Comparison Test, *** = p < 0.001) (A). Sample traces of EJP recordings taken at 1 Hz, shown in the same order as listed for the graphs (B). mEJP frequency was significantly lower for jar³²²/Df(3R)crb87-5 and jar³²²/Df(3R)crb87-5 MN larvae compared to the control larvae (Dunnett's Multiple Comparison Test, *** = p < 0.001) (C). There was no significant difference in mEJP amplitude between jar mutants and the control (ANOVA, p > 0.05) (D). Sample traces of electrophysiological recordings from muscles 6/7 over 2 seconds, shown in the same order as listed for the graphs (E). Bars represent mean ± SEM.