Table 3.
Comparison of the activities of serum hepatic enzymes in the quartile hair arsenic exposure groups by multivariate linear regression analyses
| Dependent variables | Independent variable (Hair As) |
Before adjustment for covariates | After adjustment for covariatesb | ||||
|---|---|---|---|---|---|---|---|
| Coefficient (95% CI) | p-value (t-test) | R2 | Coefficient (95% CI) | p-value (t-test) | R2 | ||
| ALP | Lowest (0.05 - 1.43) |
- | - | 0.135 | - | - | 0.172 |
| Low (1.57 - 2.80) |
0.040 (-0.009 - 0.089) |
0.11 | 0.028 (-0.023 - 0.078) |
0.28 | |||
| Medium (2.81 - 5.52) |
0.049 (0.000 - 0.098) |
0.05 | 0.044 (-0.005 - 0.093) |
0.08 | |||
| High (5.66 - 37.24) |
0.134 (0.085 - 0.183) |
< 0.01 | 0.117 (0.066 - 0.168) |
< 0.01 | |||
| AST | Lowest (0.05 - 1.43) |
- | - | 0.097 | - | - | 0.150 |
| Low (1.57 - 2.80) |
0.018 (-0.029 - 0.064) |
0.46 | 0.028 (-0.020 - 0.075) |
0.25 | |||
| Medium (2.81 - 5.52) |
0.054 (0.007 - 0.10) |
< 0.05 | 0.054 (0.008 - 0.099) |
< 0.05 | |||
| High (5.66 - 37.24) |
0.100 (0.053 - 0.146) |
< 0.01 | 0.096 (0.049 - 0.144) |
< 0.01 | |||
| ALT | Lowest (0.05 - 1.43) |
- | - | 0.079 | - | - | 0.165 |
| Low (1.57 - 2.80) |
0.037 (-0.038 - 0.111) |
0.33 | 0.064 (-0.010 - 0.139) |
0.09 | |||
| Medium (2.81 - 5.52) |
0.084 (0.010 - 0.159) |
< 0.05 | 0.086 (0.014 - 0.158) |
< 0.05 | |||
| High (5.66 - 37.24) |
0.146 (0.071 - 0.220) |
< 0.01 | 0.151 (0.076 - 0.225) |
< 0.01 | |||
bAdjusted for age, sex, BMI, smoking habit and skin lesions; Log-transformed dependent and independent variables were used; Degrees of freedom (df) before and after adjustments were made for covariates, (3, 196) and (8, 191). Units of hair arsenic, μg/g; ALP, AST and ALT activities, U/L.