Table 4.
Comparison of the activities of serum hepatic enzymes in the quartile nail arsenic exposure groups by multivariate linear regression analyses
| Dependent variables | Independent variable (Nail As) |
Before adjustment for covariates | After adjustment for covariatesb | ||||
|---|---|---|---|---|---|---|---|
| Coefficient (95% CI) | p-value (t-test) | R2 | Coefficient (95% CI) | p-value (t-test) | R2 | ||
| ALP | Lowest (0.15 - 3.17) |
- | - | 0.120 | - | - | 0.146 |
| Low (3.21 - 6.25) |
0.043 (-0.007 - 0.092) |
0.09 | 0.037 (-0.014 - 0.088) |
0.15 | |||
| Medium (6.26 - 11.27) |
0.071 (0.021 - 0.121) |
< 0.01 | 0.057 (0.005 - 0.110) |
< 0.05 | |||
| High (11.4 - 37.42) |
0.127 (0.077 - 0.177) |
< 0.01 | 0.109 (0.055 - 0.163) |
< 0.01 | |||
| AST | Lowest (0.15 - 3.17) |
- | - | 0.049 | - | - | 0.116 |
| Low (3.21 - 6.25) |
- 0.014 (-0.062 - 0.034) |
0.57 | - 0.007 (-0.055 - 0.040) |
0.77 | |||
| Medium (6.26 - 11.27) |
0.005 (-0.042 - 0.053) |
0.83 | 0.010 (-0.039 - 0.060) |
0.68 | |||
| High (11.4 - 37.42) |
0.058 (0.010 - 0.105) |
< 0.05 | 0.062 (0.012 - 0.113) |
< 0.05 | |||
| ALT | Lowest (0.15 - 3.17) |
- | - | 0.012 | - | - | 0.113 |
| Low (3.21 - 6.25) |
0.027 (-0.050 - 0.104) |
0.50 | 0.043 (-0.033 - 0.118) |
0.27 | |||
| Medium (6.26 - 11.27) |
0.029 (-0.048 - 0.106) |
0.46 | 0.055 (-0.024 - 0.133) |
0.17 | |||
| High (11.4 - 37.42) |
0.061 (-0.016 - 0.138) |
0.12 | 0.084 (0.004 - 0.165) |
< 0.05 | |||
bAdjusted for age, sex, BMI, smoking habit and skin lesions; Log-transformed dependent and independent variables were used; Degrees of freedom (df) before and after adjustments were made for covariates, (3, 196) and (8, 191). Units of nail arsenic, μg/g; ALP, AST and ALT activities, U/L.