Table 1.
Baseline Data in Look AHEAD Genetic cohort by ethnic group
| Variable | Non-Hispanic white Americans | African American | Hispanics | P value* | ||||||
|---|---|---|---|---|---|---|---|---|---|---|
| n | Mean | 95% CI | N | Mean | 95% CI | n | Mean | 95% CI | ||
| Female (%) | 2023 | 50.2 | - | 436 | 76.6 | - | 142 | 64.8 | - | |
| Insulin Use (%) | 2023 | 17.0 | - | 436 | 22.9 | - | 142 | 19.7 | - | |
| Statin Use (%) | 2023 | 50.1 | - | 436 | 37.6 | - | 142 | 38.0 | - | |
| Metabolic Syndrome (%) | 2023 | 95.4 | - | 436 | 76.6 | - | 142 | 64.8 | - | |
| Hypertension (%) | 2023 | 84.9 | - | 436 | 89.5 | - | 142 | 81.0 | - | |
| Age (years) | 2023 | 59.47 | (59.17, 59.77) | 436 | 58.40 | (57.97, 58.83) | 142 | 57.32 | (56.46, 58.19) | < 0.001 |
| HbA1c (%) | 2023 | 7.17 | (7.12, 7.21) | 436 | 7.34 | (7.27, 7.41) | 142 | 7.52 | (7.38, 7.66) | < 0.001 |
| Weight (lbs) | 2023 | 223.85 | (222.28, 255.44) | 436 | 220.83 | (218.54, 223.14) | 142 | 217.85 | (213.36, 222.43) | 0.021 |
| BMI (kg/m2) | 2023 | 35.88 | (35.65, 36.11) | 436 | 35.93 | (35.58, 36.29) | 142 | 35.99 | (35.29, 36.70) | 0.790 |
| Waist circumference (cm) | 2020 | 114.98 | (114.42, 115.55) | 436 | 113.17 | (112.34, 114.00) | 142 | 111.38 | (109.77, 113.01) | < 0.001 |
| Triglyceride (mmol/L) | 2023 | 1.87 | (1.82, 019) | 436 | 1.57 | (1.52, 1.62) | 142 | 1.32 | (1.23, 1.41) | < 0.001 |
| LDL-cholesterol (mmol/L) | 1975 | 2.77 | (2.74, 2.80) | 427 | 2.80 | (2.75, 2.86) | 138 | 2.84 | (2.73, 2.94) | 0.269 |
| HDL-cholesterol (mmol/L) | 1975 | 1.06 | (1.05, 1.07) | 427 | 1.11 | (1.09, 1.13) | 138 | 1.16 | (1.13, 1.20) | < 0.001 |
| Cholesterol (mmol/L) | 1975 | 4.85 | (4.81, 4.89) | 427 | 4.81 | (4.75, 4.87) | 138 | 4.77 | (4.66, 4.89) | 0.242 |
| Fasting Glucose (mmol/L) | 1975 | 8.32 | (8.22, 8.42) | 427 | 8.09 | (7.95, 8.24) | 138 | 7.88 | (7.60, 8.16) | 0.007 |
| SBP (mm/Hg) | 1993 | 128.82 | (128.06, 129.58) | 432 | 129.52 | (128.39, 130.66) | 140 | 130.23 | (127.98, 132.52) | 0.268 |
| DBP (mm/Hg) | 1993 | 69.41 | (69.03, 69.80) | 432 | 70.98 | (70.4, 71.57) | 140 | 72.59 | (71.41, 73.79) | < 0.001 |
Data presented is mean (95% confidence intervals), adjusted for age and gender;* overall comparison between the three ethnic groups after adjustment for gender.