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Genotypic prediction of HIV-1 tropism by a subtype D specific algorithm compared to the observed phenotype
| TTT | Concordance | Genotypic Prediction | ||||
|---|---|---|---|---|---|---|
| Genotypic tool | R5 | R5X4/X4 | Sena | Speb | ||
| Combined 11/25 and net charge rules for subtype D | R5 | 21 | 1 | 92% | 75% | 95% |
| X4 | 1 | 3 | κ = 0.70 (p < 0.001) | |||
aSen: sensitivity for predicting CXCR4-using viruses
bSpe: specificity for predicting CXCR4-using viruses
κ: kappa coefficient.
