Table 1.
Demographics of high-risk breast cancer subjects
| Unaffected | Affected | p-value | |
|---|---|---|---|
| N = 56 | N = 82 | ||
| Age at Diagnosis Range (yrs) | 25-78 | 27-79 | |
| Mean Age at Diagnosis (yrs) | 47.44 | 44.73 | 0.19* |
| Median Age at Diagnosis (yrs) | 50 | 45 | |
| Standard Deviation | 13.63 | 10.65 | |
| Mutation | |||
| 185delAG (BRCA1) | 19 (31.6%) | 21 (24.7%) | |
| 5382insC | 4 (7.0%) | 12 (14.8%) | 0.15** |
| Other | 35 (61.4%) | 49 (60.5%) | 0.57** |
| Relationship Information | |||
| Num. Pairs | |||
| Sister-Sister | 15 | ||
| Other relationship | |||
| i.e. Aunt-Niece and Cousins | 16 | ||
*Unpaired t-test, t = 1.13, df = 136
**Determined by Fisher's exact test.