Table 2.
Genetic Model | Genotype | Low | High | OR* | 95% CI | p | ||||
---|---|---|---|---|---|---|---|---|---|---|
BRCA1 | n = 44 | % | n = 66 | % | ||||||
E1038R | Co-Dominant | TT | 20 | 18.2% | 23 | 20.9% | 1.00 | |||
CT | 18 | 16.4% | 32 | 29.1% | 1.08 | 0.45 - 2.64 | ||||
CC | 6 | 5.5% | 11 | 10.0% | 1.07 | 0.32 - 3.60 | 0.46 | |||
Dominant | CC/CT | 24 | 21.8% | 43 | 39.1% | 1.60 | 0.47 - 2.47 | 0.34 | ||
Log-Additive | 0.64 - 1.94 | 0.70 | ||||||||
D693N | Dominant | CC | 41 | 37.3% | 57 | 51.8% | 1.00 | |||
CT | 1 | 0.9% | 9 | 8.2% | 6.03 | 0.69 - 52.02 | 0.10 | |||
Q356R | Dominant | TT | 32 | 29.1% | 56 | 50.9% | 1.00 | |||
CT | 11 | 10.0% | 9 | 8.2% | 0.57 | 0.20 - 1.60 | 0.28 | |||
Rad51 | 5' UTR 135G>C | |||||||||
Dominant | GG | 36 | 35.0% | 35 | 34.0% | 1.00 | ||||
CC/CG | 7 | 6.8% | 25 | 24.3% | 3.64 | 1.38 - 9.54 | 0.03 |
*Adjusted for age