Table 3.

Relationship between mutagen sensitivity and polymorphisms in BRCA1 185delAG and 5382insC mutations carriers who are unrelated

		Genotype	Low		High		Fisher's p
185delAG			n = 8	%	n = 17	%
	E1038G	TT	0	0	0	0
		CT	3	20.0%	8	53.3%
		CC	3	20.0%	2	13.3%	0.25
	D693N	CC	4	28.6%	8	57.1%
		CT	0	0.0%	2	14.3%	>0.99
	Q356R	TT	5	17.9%	7	25.0%
		CT	1	3.6%	1	3.6%	0.45
	Rad51	GG	8	32.0%	10	40.0%
		CG/CC	0	0.0%	7	28.0%	0.06
			Low		High		Fisher's p
5382insC			n = 3	%	n = 8	%
	E1038G	TT	2	28.6%	3	42.9%
		CT/CC	0	0.0%	2	28.6%	>0.99
	D693N	CC	2	28.6%	4	57.1%
		CT	0	0.0%	1	14.3%	0.73